A shake-before-use mist serum with oil and jelly layers. The 2.02 fl oz Amazon US listing corresponds to the 60 mL option; Medicube’s U.S. page also offers a 100 mL size.
Dual-layer oil-and-jelly mist serum · shake before use
PDRN label detail
Sodium DNA 1,081 ppm in the ingredient list
Spray distance
Close for a richer spray · 10–20 cm for a finer mist
Consider this if you want a spray format with both an oil and jelly layer and prefer to vary the application distance. The ingredient list includes meadowfoam and sunflower seed oils, as well as lemongrass leaf oil and anise fruit/seed oil.
Based on brand information and published sources, not a hands-on review.
01 / TEXTURE
Texture and format
Brand description
Medicube describes an oil-and-jelly dual-layer formula.
03 / YOUR ROUTINE
How to use it in your routine
Official directions
Shake well to blend the layers before each use. Spray close to the skin for a richer, serum-like application, or from 10–20 cm away for a finer mist. Medicube says it can be used after cleansing or when skin feels dry or dull, including over makeup.
Medicube's '99% purity Salmon PDRN' wording is not a stated 99% concentration in the finished formula; the list separately states Sodium DNA at 1,081 ppm. Its page gives clinical percentages but limited study detail, so they are not presented as expected results.
The bottle has an oil layer and a jelly layer. Medicube says to shake it before use so the layers mix. Its U.S. page offers 60 mL and 100 mL sizes; the 2.02 fl oz Amazon US listing corresponds to the 60 mL option. Check the selected size when ordering.
How close should you spray?
Medicube recommends spraying close to the skin for a richer, serum-like application, or from 10–20 cm away for a finer veil. The brand also says it can be used after cleansing or when skin feels dry or dull, including over makeup. These directions describe how to apply the mist; they do not establish that it replaces moisturizer or sunscreen.
What do the PDRN numbers mean?
Medicube describes the ingredient as “99% purity Salmon PDRN”; that is a purity statement about the ingredient, not a claim that 99% of the finished formula is PDRN. The U.S. ingredient list separately gives Sodium DNA at 1,081 ppm and Collagen Water at 80.9%. These figures describe different things.
Which ingredients does the mist list?
The list includes niacinamide, Sodium DNA, collagen, hyaluronic acid forms, glutathione, ceramide NP and several oils. It also names lemongrass leaf oil and anise fruit/seed oil. If botanical oils or fragrance-related ingredients matter in your routine, check the full list and the package you receive.
What do the reported study percentages mean?
Medicube reports one-use changes in hydration, radiance and plumpness and names the Global Institute of Dermatological Sciences. The product page does not give the participant count, control, measurement method or full protocol. Treat the figures as manufacturer-reported study results, not a prediction for your skin.
Selected ingredients · linked English product listing
Ingredient
Role or purpose
Formula detail
Sodium DNA
Named PDRN ingredient
1,081 ppm in the official ingredient list; distinct from the brand's purity wording.
Collagen Water
Named base ingredient
80.9% stated in the official product description.
Meadowfoam and sunflower oils
Listed formula ingredients
Both appear in the U.S. ingredient list.
Lemongrass leaf oil · Anise fruit/seed oil
Listed botanical oils
Check the full list if you avoid these ingredients.
Official ingredient list ↗. Ingredient roles explain the formula. See the sourced product information and evidence limits below.
BRAND-REPORTED EVIDENCE
Official formula and use information
The brand reports one-use clinical percentages and names a testing institute, but the product page omits participant count, control, measurement method and full protocol. The percentages do not predict an individual result.
No. “99% purity” describes the ingredient’s stated purity, not the percentage of the finished formula. The ingredient list separately states Sodium DNA at 1,081 ppm.
Both are leave-on spray products, but this medicube formula has separately described oil and jelly layers that the brand says to shake before use. Haruharu's existing Black Rice Probiotics Barrier 2% NAD+ Serum Mist is a separate 80 mL product. Compare their full ingredient lists and directions; the shared spray format does not mean the formulas or results are interchangeable.
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Products with overlapping ingredient lists
Calculations use complete ingredient lists for the stated market and product version. Listed names do not establish concentrations, equivalent effects or allergy suitability.
Explore products in the same use group with overlapping ingredient lists, then compare their texture, directions and ingredient differences.
How are candidates selected?
Candidates share the page’s language, market context and use group and have a complete ingredient list available. Names are normalized for spacing and reviewed synonyms; duplicate names count once.
The default order divides shared names by all distinct names across both lists: 10 shared names out of 20 distinct names gives 10 ÷ 20. You can instead order by the number of shared names. Up to five candidates are shown.
Ingredient overlap does not establish equivalent effects or a cheaper substitute. Concentrations, ingredient order, finished-product tests and feel are not part of this calculation. Missing lists are not treated as missing ingredients.